New FDA-Approved Drug for Amyotrophic Lateral Sclerosis (ALS)

First new FDA-approved drug for ALS in 22 years... the antioxidant Edaravone (Radicava).

 

Edaravone

  • First new drug for ALS in 22 years!!!
  • Antioxidant Edaravone (brand name: Radicava)
  • Mechanism is not fully known but is thought to confer neuroprotection because of its free-radical scavenging activity.
    • It's NOT a cure... but...
    • Edaravone was shown to slow the progression of ALS when started early in the disease course.
  • The only other drug for ALS is Riluzole which was approved in 1995.

 

 

Associated article: Dancing Tongue

Category: CNS

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