Lymphoma Translocation

 

What do most of the major translocations for non-Hodgkins lymphoma (NHL) have in common?

 

                                                  Burkitt NHL          t(8;14)

                                                  Follicular NHL     t(14;18)

                                                  Mantle cell NHL  t(11;14)

They have translocations involving chromosome 14 which is the Immunoglobulin Heavy chain (IgH).

 

 

The name has the answer....  In IgH the "I" looks like the number 1 and you can fit a number 4 in the H!

 

Thanks to Dr. Eduardo Martinez del Campo Oviedo

Copyright ©2012 Thunderpath Media Inc. All rights reserved.

 

Category: Hematology Mnemonics

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